Frontiers in Zoology

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The exceptional stem cell system of Macrostomum lignano: Screening for gene expression and studying cell proliferation by hydroxyurea treatment and irradiation

Daniela Pfister, Katrien De Mulder, Isabelle Philipp, Georg Kuales, Martina Hrouda, Paul Eichberger, Gaetan Borgonie, Volker Hartenstein and Peter Ladurner*

Frontiers in Zoology 2007, 4:9 doi:10.1186/1742-9994-4-9

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Research article   Open Access Highly Accessed

Characterization of the stem cell system of the acoel Isodiametra pulchra

Katrien De Mulder, Georg Kuales, Daniela Pfister, Maxime Willems, Bernhard Egger, Willi Salvenmoser, Marlene Thaler, Anne-Kathrin Gorny, Martina Hrouda, Gaƫtan Borgonie, Peter Ladurner BMC Developmental Biology 2009, 9:69 (18 December 2009)

The acoel Isodiametra pulchra has neoblasts that are potent stem cells crucial for tissue homeostasis, development and regeneration, and is a new model organism for studying development in this primitive bilaterian phylum.

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Melav2, an elav-like gene, is essential for spermatid differentiation in the flatworm Macrostomum lignano

Kiyono Sekii, Willi Salvenmoser, Katrien De Mulder, Lukas Scharer, Peter Ladurner BMC Developmental Biology 2009, 9:62 (8 December 2009)

An elav-like gene, melav-2, is exclusively expressed in the testis of the flatworm Macrostomum lignano and its knockdown by RNAi induces precocious chromatin condensation and aberrant cell elongation during spermiogenesis, resulting in immature spermatids and male sterility.

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Demographic analysis reveals gradual senescence in the flatworm Macrostomum lignano

Stijn Mouton, Maxime Willems, Patricia Back, Bart P Braeckman, Gaetan Borgonie Frontiers in Zoology 2009, 6:15 (30 July 2009)