Figure 5.

Influence of irradiation on the stem cell population as shown by macpiwi expression in Macrostomum. (A) Macpiwi expression in control adult. Signal was present in testes (t), ovaries (o), developing eggs (de) as well as at a basic level in somatic stem cells. (B) Expression of macpiwi in somatic stem cells 3 hours postirradiation. (C) After 1 day recovering from irradiation, macpiwi expression in somatic stem cells is lacking, but present in the gonads. (D) Macpiwi expression 1 week postirradiation (80 Gray). Note the complete loss of macpiwi expression in testis. (E) Macpiwi expression resembles default expression pattern 3 weeks postirradiation (80 Gray). scalebar 100 μm.